A peaceful dying experience with MDMA

My friend George D.  told me about the deeply transformative experience his aged, raging and demented mother had in the last months of her life – after he gave her a single dose of MDMA. Neither George nor I would normally ever condone giving someone a dose of this (or any) medicine without their full knowledge and consent. It will be clear from reading this experience, that his mother would have been incapable of receiving or understanding any verbal explanations he might have given. As it was, he persuaded her to take it by telling her that it was “heart-medicine”  – which turned out to be true in an unexpectedly profound and beautiful way. I’m publishing this story here with George’s permission – to offer hope that others too might find their way to a peaceful dying.

The time of this experience was November of 2007 and the setting was a traditional family home in a Greek village. This was the house my mother had grown up in before emigrating to the United States as a young lady. The room she stayed in was exactly like she had left it seventy five years previously, with the same bed and wall decorations. Along with my wife Stephanie and our three children, we had brought her back to this house when she was around 94 and were taking care of her as needed.

She was fairly well until the last year when her health deteriorated rapidly. No longer could she walk without trembling, nor do much in the way of independent action and thought. She was 99 years old and made it clear that she wanted to die here in her home and be buried with her ancestors.  Yet her anger at us and the world in general continued to consume her passion.

It was on such an evening of her cursing my existence that I reflected deeply on her situation. Under normal circumstances, I would find it unethical to give someone a drug without explaining to them the purpose and its possible side effects. But in this case of her being caught in such a web of emotional pain and negativity, I decided to give her the one dose of MDMA (or Ecstasy) which I was saving for a special occasion.

As she grabbed the little white pill that I gave her, my mother hissed the question “what was I giving her,” to which I replied that it was “heart medicine”. Her retort was that I had been giving her poison to her heart all my life and here was one more intention of mine to kill her. I took a deep breath and felt the fear of a premonition that her experience could be a very very bad one. It would then be a decision that could haunt me for the rest of my life. It turned out to be true that that decision has indeed had a significant impact on my life, but with a far better outcome than even I anticipated. After giving her the “heart medicine” I said my good nights and left her alone.

Checking in half an hour later, I found her sitting on her bed gazing at an icon of the Virgin Mary. The fact that I saw her smiling was a hint that a profound event was manifesting. When I asked her how she felt, she softly said that “there were angels flying around the room.” That was a trigger for me to run upstairs, wake up our son John and tell him to come downstairs with his guitar – that we had important work to do with his grandmother.

For the next few hours we exchanged hugs with my mother and also shared her delight in listening to CDs of both Greek Orthodox religious hymns as well as her favorite Greek folk music. At times John would strum a few chords on his guitar while we sang about how much we loved her. When my wife Stephanie came downstairs to be part of the miracle, she asked my mother how she was doing – to which my mom said in a very sweet tone, “this night will never end.” My mother was no longer judgmental and mean. Her words, smiles and touch were soft and loving. It was a blessing for all of us.

There was more amazement ahead. From that night on, for the last seven months of her life, my mother dropped her fear-based masking and let her heart express itself in a very beautiful way. No longer would she judge or criticize anyone but instead say loving remarks. She would smile and ask to kiss us regularly every day. She no longer demanded I cut my beard but asked if she could stroke it. She had previously refused to let her granddaughters take her to the village in her wheelchair – now she welcomed their brushing her hair, putting a flower in back of her ear and taking her out for ice cream.

What matters most is that one experience with the “heart-medicine” brought lasting comfort in her remaining life and could well have helped her soul cross over more gently. The circle was more complete and her grandchildren will always remember her as being at peace with herself and the world. And of course, so will I.

The Work of Terence and Dennis McKenna – An Appreciation

Reading the fraternal autobiography, The Brotherhood of the Screaming Abyss,  was for me  both fascinating and moving, as I was and remain close friends with both the brothers, have shared stimulating conversations and psychedelic explorations with them, and was deeply saddened by Terence’s early death. Terence became known for his scintillating eloquence and Irish gift of the gab, like my old friend from an earlier generation Timothy Leary. His scintillating flights of the imagination, mixing far-out speculative science and arcane scholarship, delivered in his characteristic dead-pan nasally inflected voice – have astonished and delighted thousands – and remain in disembodied recordings circulating worldwide on the internet.

As his brother Dennis writes “Terence channeled the logos of the age. Silver-tongued and a riveting speaker, he articulated the concepts that his fans groped for but could not express, and did so in a witty, disarming way. He was the gnomic trickster and bard, an elfin comedian delivering the cosmic punch line, even as he assured us we were all in on the cosmic joke.” Especially, one might add, if you followed his advice and continued to take what he liked to call  “heroic doses” of psychoactive mushrooms and DMT.

Dennis, who was close to and admired his eloquent and imaginative older brother, took on a different role in society, after the two intrepid explorers returned from the shamanic-alchemical-cosmic folie-a-deux described as “the experiment at La Chorerra,” in their joint autobiography The Invisible Landscape.  Dennis went back to school, got a Ph.D. in plant biochemistry and embarked on a career as research scientist in botanical medicine. His writing, in this dual autobiography, is enormously engaging, brilliantly articulating complex issues of natural history, while dealing honestly and humbly  with the personal, familial and professional challenges with which he was confronted.

Terence once commented to me in a conversation, that while he was known as the more eloquent speaker and captivating story-teller, his brother Dennis was, in his view, the more profound thinker and scientist. “His mind goes deep into matter,” he said with obvious admiration. Indeed,  Dennis has carved out a significant career as a consultant in the development of new botanical medicines, with a slew of research publications to his credit. I’ve always loved listening to his lucid and articulate explanations of complex concepts in molecular biology and entheobotany.

One of the  most exciting passages in Dennis’s book, to my mind,  is in the chapter where he describes the research work he and two colleagues did on the chemistry and pharmacology of ayahuasca for the Brazilian UDV church – work that resulted in several scientific papers published in the botanical and pharmacological literature.  He subsequently participated in a group session with ayahuasca (or hoasca as the church calls it) for several hundred participants  – a ceremony I also attended. With the help of a concoction of the visionary vine, Dennis found himself identified as a sentient water molecule and was shown and actually subjectively experienced the entire process of photosynthesis, step by step. As a trained plant biochemist, he was able to identify and name the different processes he had come to understand objectively, as he was experiencing them subjectively, from the point of view of a single drop of water.

 “I knew that I had been give an inestimable gift, a piece of gnosis and wisdom straight from the heart-mind of planetary intelligence, conveyed in visions and thought by an infinitely wise, incredibly ancient, and enormously compassionate ‘ambassador’ to the human community.”

This was perhaps a core vision of Dennis’ life as a scientist, presaging, like the work of Jeremy Narby, a time when the instrumental external observations of material and natural scientists will be supplemented by and compared with the interior observations of those same scientists in sensitized and expanded states of consciousness.

I find a comparable core vision statement of Terence’s life work in the introduction he wrote to the Magic Mushroom Growers Guide, which the two brothers published, under pseudonyms, in 1976. This guide itself is perhaps one of the most important contributions the two brothers made to the advancement of culture – describing a relatively simple process of growing the psilocybe mushrooms from spores in glass jars – thereby making these vision mushrooms accessible to millions and obviating the plundering invasions of the mountains of Oaxaca by fungophile hippies.

 

The experiment at La Chorera

In his fraternal autobiography Dennis is frank about the early unusual degree of closeness of the two brothers, triggered perhaps by the death of their mother when they were teens, and certainly fueled by the daily consumption of huge amounts of cannabis, as they made their early 1960s migration from small town Colorado to the West Coast hippie carnival. In 1971, the two brothers, young men in the twenties, ventured on a journey to Colombia, together with several friends, to search for ayahuasca, the legendary shamanic hallucinogen,  then relatively unknown. What they found instead were large quantities of high potency psilocybe mushrooms, with which they began what they called “the experiment at La Chorera.” This was described in their co-authored 1975 book The Invisible Landscape.

Basically, the experiment consisted of both of them repeatedly ingesting rather large quantities of the mushrooms, listening to a kind of interior, alien-sounding, buzzing or humming sound, and then reproducing that sound vocally to induce a lasting expanded state of consciousness. They had a complex theory, which they were discussing and elaborating in intense daily speculative conversations,  of how the psilocybin could activate endogenous tryptamines in the brain and create some kind of “holo-cybernetic unit of superconductive genetic material, activated via tryptamine harmonic interference.”

Following the ingestion of an enormous overdose of nineteen psilocybe mushrooms (a “normal” dose being perhaps three to six), plus continuous smoking of cannabis and also some ayahuasca that Terence had brewed up, and experimenting with prolonged vocal ululations,  Dennis developed a thought-hallucination,  sympathetically supported by Terence,  in which he felt they both were in touch with a “Teacher” of some kind.  This “Teacher” would guide them to …

…generate a hologram, which would begin to broadcast the information stored in the DNA, making the data both comprehensible to thought and open to manipulation by thought. If the experiment worked, one of us in the near vicinity would be turned into a DNA radio, transmitting the collective knowledge of all earthly life, all the time. This was the information that was downloaded to me by the Teacher, a recipe for constructing a hyper-dimensional artifact that would bind four dimensions into three and thereby end history. An object made of mushrooms, bark (from ayahuasca) and my own DNA, welded together by the sound of my voice.

While Dennis was being flooded by these eschatological thought-hallucinations, and furiously scribbling notes about the information he was “downloading,” his brother Terence was playing the supportive role of maintaining contact and communication, refusing the urgings of their companions that Dennis be committed to a mental institution.

Dennis writes, in his 2012 autobiography,

“in retrospect, I see how our conceits embodied a paradox of psychedelic experience. ..on one level we understood that a molecule doesn’t contain the trip. Rather, the trip is an interaction between a living organism and molecule’s pharmacological properties. Those properties may be inherent to the drug, but the trip itself is not. .. We got that, sort of. But in our delusion, if that’s what it was, we also embraced a conflicting view: We believed an intelligent entity resided in the drug, or at least somehow communicated to us through it. Even as we theorized about the 4-D expression of the drug – that the trip could somehow be expressed on its exterior by rotation through the fourth dimension – we were assuming on another level that a being of some sort was directing the trip. We weren’t the first or the last to make that “mistake.” After all, this is very close to shamanistic views of psychedelic experience, in which the drug speaks through a skilled practitioner.”

Here, I believe, was a crucial turning point in the development of their shared delusion, due to the brothers’ inevitable conditioning and commitment to the materialist worldview, as children of their time and their place of origin.   In the shamanistic worldview, the visions do not come  from the drug,  nor from the plant, nor even from the shaman guide who speaks or sings (whom the two brothers in any event did not have).  The visions  come from the spirits associated with the plants who communicate to the shamanic practitioner or explorer.   The shaman usually has established relationships with specific plant and animal spirits through his or her practice and training, and is thus able to decode the messages and visions “coming through” (or “being downloaded”) and translate them into the locally appropriate action or teaching.

As a committed materialist in good standing with his profession,  Dennis, in his autobiography, offers his support of the reductionist credo, though he clearly has some reservations:

“These substances did none of these things. The human mind-brain created these experiences. At La Chorrera, the psilocybin somehow triggered metabolic processes that caused a part of our brains to be experienced not as part of the self, but as the “other” – a separate, intelligent entity that seemed to be downloading a great many peculiar ideas into our consciousness. That’s the reductionist perspective. Is it true? I honestly can’t say, even today. If either is true, or is the alternative  true, that there are actually entities in hyperspace that can communicate with us via something akin to telepathy when the brain is affected by large amount of tryptamine – that’s a hypothesis worth testing.”(p. 248)

Actually, from my perspective, having long ago abandoned the reductionist empiricism of modern science and become a “radical empiricist” in the sense of William James, I  would say one needs to first simply describe the experiences – and later, separately, speculate about their meanings and implications for our existing worldview. Easier said than done, I agree, considering the irrepressible excitement of new discoveries. You have to hold the theoretical speculations in abeyance until the intensity of the experiential download diminishes somewhat, and you can calmly reflect on the experience.

Certainly, by now there are enough individuals in the psychedelic shamanic subculture who have had multiple experiences of intelligent communications with spirits, and who have learned, with practice, to decipher these communications and utilize them in their projects of healing or creative expression. However, our two young explorers from Colorado in the early 1960s were just beginning their life-long journeys as psychonauts.

Over the years, I have been around dozens of people (myself included) who, as a result of ill-prepared ingestion of high-dose psychedelics,  got temporarily caught in a delusional thought-system – often including profound insights,  but over-generalized as to their significance. Delusions of grandeur are mixed with genuine amazement at the bewildering grandeur and magnificence of the actual world of nature all around us. There are several examples of such delusional over-generalization in the text that Dennis wrote at the time he was setting himself up for the high-dose experiment.

“In the final Stone the tryptamines act as a superconductive antenna to pick up on all cosmic energy in space and time.”

Not just picking up some cosmic energy, but all.

Or, “It will constitute the 4-D holographic memory of the device, and will contain and explicate the genetic history of all species.”

As if picking up the genetic history of one species or even one individual wouldn’t be enough.

Over-generalization is part of the delusions of grandeur – perhaps a special feature of high-dose psychedelic drug experiences. I recall many times at our communal experiment in Millbrook, NY,  and afterwards, being cornered by a wild-eyed hippie wanting to impart the ultimate cosmic secret he had just been granted on his trip, that he was sure everyone would appreciate for its earth-shattering profundity.

Receiving such visions does seem of overwhelming importance and it is – at least to the individual concerned. Others, like family members or professionals, may not appreciate the cosmic significance of the vision/hallucination and are more likely to be alarmed by the tenuous nature of the individual’s connections to ordinary reality. Visionaries are notorious for appearing to others like madmen.

As a psychologist, I do not believe that what the brothers experienced was schizophrenia of either variety.  The latter is characterized by  fragmented ideation and inability to think rationally. What the McKenna brothers experienced was a glimpse into what shamans would call the “spirit world”, and what they call “hyperspace.” There is an inexhaustible vastness of other dimensions of our universe that are always there but only accessible in special states of consciousness and/or through shamanic or yogic practice, or through special instrumentation.

And yes, their glimpse was fragmentary and yes they were unprepared, and yes they had no ready-made language to describe what they found – explorers never do. These non-ordinary reality visions can only be communicated if one has access to a worldview and a consensual language to describe them. The brothers McKenna did not have either at the time of their “experiment”  though they have both contributed significantly since then to creating an expanded worldview – Terence through his imaginative  and inspiring speculations, Dennis through his solid scientific investigations into ethnobotanical medicines and their neurochemical effects.

Reflecting on his experiences of forty years ago, the sixty-year old Dennis writes poignantly about the wild mis-adventure of his twenty-year old former self.

“The ravings of a madman, I’ll grant you that. And yet, there is also poetry here, and beauty, and a longing for redemption.  What I expressed is not that different from the vision articulated by the most compassionate and beautiful of the world’s religions: the universe will not achieve perfection until all beings have achieved enlightenment. Isn’t that what I’m saying? No doubt there is messianic delusion here; indeed, in passages a bit further on in that text I discuss my role as cosmic Antichrist. But there is also a deep wish for healing, not only of myself but of the universe. Our mother had been dead less than six months. I have to believe that much of what happened to us at La Chorrera was linked to that tragic event. So overwhelmed were we by the sense of loss, and of guilt, we were ready to tear space and time apart in order to reverse that cosmic injustice.” (p. 257).

Over the next couple of weeks Dennis put his fragmented identity-programs back into a functional order, while his brother Terence was obsessively starting to construct his own metaphysical system that later become known as Time Wave Zero. The brothers’ companions could see only psychosis and wanted to bring Dennis to a psychiatric facility – no small task considering they were in the Amazon jungle. Dennis writes he is “grateful to Terence for resisting the pressure to leave La Chorrera. He insisted that whatever was happening to us be allowed to unfold in its own time and on its own terms – there was no need for intervention beyond making sure that I didn’t wander off or hurt myself.”

Terence’s intuitive understanding of the need to let the fragmented self-system of his brother find its own way back to center and to wholeness was consonant with the teachings of psychiatrists like Ronald Laing, Stanislav Grof, John Perry and others who have championed the idea that some forms of so-called “psychosis” can be understood as the psyche’s own natural healing journey – that is best supported by others, and not cut short by psychiatric medications.

 

The aftermath of La Chorera and returning to mainstream reality

After returning to the US, the two brothers, more convinced than ever of the value of psilocybin mushrooms, wrote and published, under pseudonyms and with the collaboration of Kathleen Harrison as illustrator, the first Magic Mushroom Grower’s Guide which gave easy instructions for indoor cultivation and made the mushroom experience accessible to thousands. The brothers eventually took different career paths. Dennis went on to pursue graduate, doctoral and post-doctoral studies in plant chemistry and pharmacology, published research in the pharmacology of Amazonian psychoactive plants, and worked (still does) as a research consultant for the pharmaceutical and herbal industry. Terence, more of an auto-didact, devoted himself to ethnobotanical research and writing and became a much sought-after speaker on the lecture circuit.

In the introduction to the Mushroom Grower’s Guide booklet, Terence described a vision he received, perhaps the core and guiding vision of his life, of the interstellar origin of the mycelial nets, the true body of the mushrooms, which he believed maintain a “vast historical archive of the career of evolving intelligence on many worlds.” The mycelial networks seek habitable planets, he was told, where they can enter into symbiotic communication and exchange with intelligent species, providing that species with access to the “community of galactic intelligence.” The notion of the true form of the mushroom being the mycelial nets and the emphasis on symbiotic interactions of fungi with other species are points consistent with current scientific understanding of fungal evolution, as formulated in the work of Paul Stamets and Lynn Margulis. The idea of extra-terrestrial origin is uniquely and provocatively Terence McKenna, emissary from the world of entheogenic fungi.

In a later essay published in his book The Archaic Revival, Terence McKenna returns to elaborate on this theory, or rather the vision that he received and first recorded in the introduction to The Mushroom Growers Guide.

The mushroom was a species that did not evolve on Earth. Within the mushroom trance I was informed that once a culture has complete understanding of its genetic information, it reengineers itself for survival. The Stropharia cubensis mushroom’s version of reengineering is a mycelial network strategy when in contact with planetary surfaces and spore-dispersion strategy as a means of radiating throughout the galaxy…The other side does seem to in possession of a huge body of information drawn from the history of the galaxy…The Stropharia cubensis mushroom, if one can believe what it says in one of its moods, is a symbiote, and it desires ever deeper symbiosis with the human species. It achieved symbiosis with human society early by associating itself with domesticated cattle and through them human nomads.

He cheerfully goes on to argue against his own thesis of extra-terrestrial origin though, when he goes on to say: “I’ve recently come to suspect that the human soul is so alienated from our present culture that we treat it as an extraterrestrial. To us the most alien thing in the cosmos is the human soul.”

I personally find the thesis that extra-terrestrial sources of vast intelligence might be communicating to the human species via entheogenic plants and mushrooms quite plausible and worthy of further investigation. It is consistent with the fact that interest in UFOs and extra-terrestrial culture and contact has been growing tremendously in the second half of he 20th century, in tandem with other movements of consciousness expansion, such as psychedelics, shamanism, spiritual practices and higher states of consciousness. Harvard psychiatrist John Mack, who had made an intensive study of the UFO abduction experience, has shown, in his most recent book, Passport to the Cosmos, that reported contact and communication with alien intelligences is widespread and almost taken for granted in societies with living shamanic traditions. The notion that experiences with Amazonian hallucinogenic vines and mushrooms could facilitate or induce visions of extra-terrestrial visitors and space-ships, is also supported by the art of Pablo Amaringo, a Peruvian ayahuasquero who painted hundreds of visionary experiences, including many encounters with extra-terrestrial craft.

Terence McKenna’s thesis on the symbiotic role of entheogenic fungi was further extended in his major work, The Food of the Gods, in which he proposed that the discovery of consciousness-expanding mushrooms by our proto-hominid ancestors might have led to the development of language, higher intelligence and culture. While this thesis has been generally treated with disdain, or else ignored, by the academic establishment, it is interesting that there isn’t really a good alternative theory of the development of language or higher intelligence.  Furthermore, establishment academics are likely to be unfamiliar with the nature of psychedelic experience, and therefore hardly in a position to evaluate McKenna’s hypothesis objectively. As we know, those scientists who had not looked through a microscope or a telescope were not really qualified to evaluate the observations of those who had. The history of science is rife with similar examples.

In favor of the idea that mind-expanding plants may have played some role (if not the only one) in the evolution of language are:  (1) laboratory evidence that psilocybin and other psychedelics lower sensory thresholds, i.e. heighten acuity of sense perception, which would confer a direct adaptive advantage; (2) studies of brain areas activated during psilocybin states that show major activity in the frontal cortex, the area most involved in processing complex perceptions and thoughts; (3) evidence from subjective experience accounts that psychedelic mushrooms heighten cognitive awareness and linguistic fluidity – as, for example, in the chants of the Mexican Mazatec curandera Maria Sabina; and (4) heightened problem-solving ability, with adaptive advantages, is also suggested by the effective use of psychedelic drugs in psychotherapy and shamanic divination.  Terence McKenna’s Food of the Gods ranges far and wide through history, anthropology and around the globe in his review of sacred mind-expanding substances.  He re-examines R.G. Wasson’s hypothesis that soma, a mysterious substance deified in the Vedas, was basically the fly agaric mushroom cult, imported from Central Asia. Though historian of religion Mircea Eliade, who had written a masterful overview of shamanism, considered the use of psychoactive plants a degenerate form of religious practice, Wasson, on the basis of his experiences in Mexico with the psilocybe mushroom and his beliefs about soma, took the opposite view. Wasson held that all religious experience was originally induced by psychoactive plants and that the practices of yoga developed in India were substitute methods, created when the mushroom was no longer available to the ecstatic visionaries. McKenna comes down on the side of Wasson, but thinks soma was the psilocybe mushroom, not the fly agaric, for the main reason that the latter is only mildly and ambiguously psychedelic; however, apart from some ambiguous mushroom-shaped stones, no evidence has been found for either mushroom species existing in India.

It may be impossible to ever settle this question in the history of religion completely. But that some psychedelic plants may have played a role in the origins of some religious traditions, as well as some aspects of language (for example, bardic poetry) seems to me both probable and plausible.

Central to the argument McKenna makes for a role of psilocybe mushrooms are the facts that Stropharia cubensis grows in cow dung and that cattle were the main source of wealth and livelihood in early Neolithic cultures in Asia and Africa. When McKenna came upon the cave paintings on the Tassili plateau in the Sahara Desert of southern Algeria, he found the most impressive piece of evidence for a mushroom cult in the Neolithic period, dating from the 9th to the 7th millennium BCE. Judging from cave paintings of giant female beings, these people worshipped the Great Goddess, as did other cultures during  the Neolithic period in Old Europe and Anatolia. The people of the Tassili Plateau are described as the “Round Head” culture, because of cave paintings that show figures with rounded heads that could obviously be mushrooms. Among the surviving images there are running figures clutching fistfuls of mushrooms and a magnificent image of a giant anthropoid bee-faced goddess (the bee was also associated with the Goddess in Old Europe). The image is holding clusters of mushrooms in each hand and smaller mushrooms sprout from her arms, legs and trunk. Unmistakably, these people held mushrooms in very high regard. Terence McKenna writes,

“The contention here is that the rise of language, partnership society, and complex religious ideas may have occurred not far from the area where humans emerged – the game-filled, mushroom-dotted grasslands and savannahs of tropical and subtropical Africa. There the partnership society arose and flourished; there hunter-gatherer culture slowly gave way to domestication of animals and plants. In this milieu the psilocybin-containing mushrooms were encountered, consumed and deified. Language, poetry, ritual, and thought emerged from the darkness of the hominid mind.”

Concluding remarks

Re-reading and revisiting the works of the McKenna brothers brought to my mind an intriguing comparison with the life and times of another pair of pioneering scientist-scholar brothers from the early 19th century – Alexander and Wilhelm von Humboldt. Alexander von Humboldt was a naturalist and explorer who traveled extensively in Latin America, exploring and describing for the first time, in over 20 illustrated volumes, the biogeography, flora and fauna of the region. Wilhelm von Humboldt was a diplomat, educator and linguist, who made important contributions to the philosophy of language and the theory and practice of education in Prussia, their country of origin.

The McKenna brothers also have made significant contributions to expanding our scientific knowledge of mind-assisting plants, fungi and substances, to the flora and fauna of inner space geography, and to the new languages and concepts inevitably needed if we wish to understand the bewildering and fascinating world of psychoactive substances.

Works cited:

McKenna, Dennis, 2012. The Brotherhood of the Screaming Abyss – My Life with Terence McKenna.  St. Cloud, MN: North Star Press.

McKenna, Terence and Dennis McKenna, 1975. The Invisible Landscape: Mind, Hallucinogens and the I Ching.  NY: Seabury Press.

Oss, O.T. and Oeric, O.N., 1976. Psilocybin, Magic Mushroom Grower’s Guide. Berkeley, CA: And/Or Press.

McKenna, Terence, 1992. The Archaic Revival: Speculations on Psychedelic Mushrooms, the Amazon, Virtual Reality, UFOs, Evolution, Shamanism, the Rebirth of the Goddess, and the End of History. New York: HarperCollins.

McKenna, Terence, 1992. Food of the Gods: The Search for the Original Tree of Knowledge: A Radical History of Plants, Drugs and Human Evolution. New York: Bantam Books.

The healing virtues and schizoid politics of cannabis

More and more reports of the unexpected healing efficacy of cannabis are being distributed in the underground media. In a recent posting on Alternet,  Laura Gottesdiener relates several stories of  “miraculous” (i.e. unexplained by current science) healings with cannabis.

  • A six-year old boy with a rare form of epilepsy that involved daily seizures, inability to eat solid food or walk around, had 40 hospitalizations and was taking 22 pills daily – all to no effect. His parents began to treat their son with a liquid form of medical cannabis, which dramatically reduced the seizures, so he could eat, run and swim.
  • An 8-month old baby had a brain tumor that couldn’t be operated. Before agreeing to chemotherapy and/or radiation treatment, the parents decided to try rubbing cannabinoid oil by rubbing it into the baby’s pacifier. After two months, the reduction in tumor size was so significant, that the pediatric oncologist decided to continue that treatment rather than chemotherapy.
  •  A two-year old boy in Montana with a brain tumor was being treated with chemotherapy that made the boy blind and too sick to eat. His father gave him cannabis oil through his feeding tube, and after two weeks he could eat solid food again.
  • A recent medical research study reports evidence that cannabinoid drugs (similar in structure to cannabis) not only are effective in treating the appetite loss associated with HIV infection, but may deter the HIV virus from turning into AIDS.
  • Two American twin girls had been raised from infancy with their mother’s hate–filled Neo-Nazi ideology and as teenagers formed and performed in a pop-band called Prussian Blue. When they were diagnosed with cancer and scoliosis, they were given a cocktail of medicines that included cannabis, which gave them “a new outlook on life.” They quit crusading for Aryan power and are now working to help legalize medical cannabis.
  •  Cannabis can apparently have psychosomatic healing effects without being ingested in food or medicine, but simply by its aroma. In the 1990s in Switzerland, when regulatory authorities, hemp farmers and cannabis smokers were negotiating back and forth to find a suitable socio-legal framework for their interests in this ancient plant, there was a time when one could legally sell and buy little cloth bags of cannabis sativa leaves and flowers,  called Duftsäckli (“aroma sachets”), to be exclusively used for “aromatizing” a room or a bed. The pot smokers of course bought these and smoked the contents – until the authorities closed the regulatory loop hole. Berlin journalist and friend Mathias Broeckers wrote to me –
  • An amazing story I heard during a visit to a nursing home for senior citizens. One of the hemp activists had persuaded the staff of this nursing home to distribute cannabis aroma sachets into the beds of the seniors and also to hang additional sachets in the room. The seniors did not know that it was cannabis that was making their rooms smell so sweet, but the nursing staff was asked to note whether there was any change in the sleep patterns of the residents. And this was exactly what happened – the residents slept better and requested significant less sleep medication.

An extraordinary healing transformation also happened with one of the residents of this home who suffered from a kind of Tourettes syndrome. Anyone who passed by her as she sat in her wheelchair was berated with a stream of curses and obscenities. Normally, the staff dealt with her by keeping her heavily sedated, so that she sat in a kind of permanently somnolent daze. The staff then came upon the idea of serving her breakfast toast spread with herb-butter. This herb-butter was made according to a traditional Eastern European recipe with hemp-flowers – and the effect on the old lady was dramatic: instead of bickering and cursing anyone who approached her, she became very  friendly and even began to flirt with the mail-man who came daily. I was traveling once with the producer of this hemp-butter, when an urgent phone call came from the staff of the nursing home: they had run out of their hemp-butter supply and urgently requested more, since the old lady was driving everyone nuts with her cursing and berating.

Meanwhile, while the evidence accumulates of the therapeutic and psychological virtues of cannabis, the American political class at the federal level is turning ideological cart-wheels in order to somehow reconcile the irrefutable evidence of medical value and the increasing trend for states to legalize not only medical but recreational use – with the archaic prohibitionist mind-set inherited from decades of a so-called “war on drugs” which is blindly maintained by the hugely bloated and out-of-control military-industrial-medical-prison complex.

A tremendous contribution to popular education about the true potential medicinal virtues of cannabis is made in the recent film by Len Richmond What if Cannabis Cured Cancer?  To my mind, the most significant point made by the film is the recognition and identification of the endocannabinoid system as an integral branch of our immune system, evolved over hundreds of millions of years of evolution, as far back as invertebrates. The following quote is extracted from an internet article  - http://norml.org/library/item/introduction-to-the-endocannabinoid-system.

The endogenous cannabinoid system, named after the plant that led to its discovery, is perhaps the most important physiologic system involved in establishing and maintaining human health. Endocannabinoids and their receptors are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells. In each tissue, the cannabinoid system performs different tasks, but the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment. Cannabinoids promote homeostasis at every level of biological life, from the sub-cellular, to the organism, and perhaps to the community and beyond.

Raphael Mechoulam, the Israeli scientist whose research  identified tetrahydrocannabinol as the chief psychoactive ingredient in the cannabis plant, has summarized the action of cannabis in the body: stimulating the endogenous cannabinoid system, as relaxing (promoting rest and sleep), increasing appetite (countering nausea and wasting) and forgetting. He particularly emphasizes the importance of forgetting – since it is important to survival to not remember every detail of all of our daily experience.

One might say the capacity to forget is integral to the healing and stress-relieving virtues of cannabis – common observation supports the notion that evening pot-smokers feel relieved and relaxed with the forgetting of the stressors that bombard us all day long. Of course, this also means that you would not want to consume cannabis when you are a student in a learning situation, where you need to remember details of facts and figures. Whether or not cannabis suppresses actual dreaming and the REM sleep associated with dreaming has not been definitely established.  It lessens dream recall, though this apparently comes back, when one stops smoking weed, as I have also confirmed.  I remember Terence McKenna telling me that when he discontinued his almost daily consumption of cannabis, he would be experience a veritable barrage of remembered dreams on awakening.

From personal and shared observation I would add two further aspects to the list of cannabis actions on the human body-mind complex – sensory pleasure and humor. The enhancement of sensory enjoyment is recognized in the heightened taste pleasure with eating, and also the heightened sensual pleasure of erotic contact. The heightened auditory pleasure induced by cannabis is well known to jazz musicians, who were perhaps the first to introduce the plant into popular culture. This effect may be caused by a sense of time dilation, giving the listener seemingly more time to appreciate the subtle variations of tone and rhythm in a piece of music.

The stimulating effect of cannabis on humor and laughter is too well known to require much proof. In the film Can Cannabis Cure Cancer, some of the interview subjects can barely contain their veritable fits of laughter. Whether thus implies stimulation of a humor center in the brain, is unknown,  but we can definitely assume it is connected to the stress-relieving and healing effects. “Laughter is the best medicine” as the old saying goes.

In an old R. Crumb cartoon that appeared sometime in the sixties, two very stoned-looking dudes are sitting on a porch in a small Western town, and a motorcyclist who has evidently just roared through town, is on the way out. One of the dudes turns to the other and says – “Man, I thought he’d never leave.”

JFK, Mary Pinchot Meyer and the Leary Connection

Over two thousand books have been written about the life and death of John F. Kennedy almost 50 years ago and 60% of the American people don’t believe the “lone assassin” theory espoused by the official Warren Commission report. It’s interesting to reflect on the fact that if the real assassins have not been brought to justice, they have been and still are, if alive, “hiding in plain sight.” A fractious consensus among assassination researchers points to multiple, complex conspiracies involving elements in the CIA, the military, the mob and Cuban exile groups – all of whom had demonstrated antagonism against the President, thus the motive and the means to carry out the crime.

I am going to discuss two recently published books: (1) David Talbot’s BrothersThe Hidden History of the Kennedy Years (2007) and (2) Peter Janney’s Mary’s Mosaic – The CIA Conspiracy to Murder John F. Kennedy, Mary Pinchot Meyer, and Their Vision for World Peace (2012). Both are extensively documented and annotated books of over 400 pages, telling complex stories impossible to summarize. I will follow the example of Howard Zinn, author of A People’s History of the United States, and state out front the view that I have come to hold, so that the reader can know what my bias is, rather than trying to pretend I don’t have one. I have come to believe that the multiple assassinations of leaders (JFK, RFK, MLK, Malcolm X to name only four of the most prominent) that occurred in the 1960s signaled the end of the American republic and the establishment of a military-industrial empire, governed according to increasingly secretive, fascistic and militaristic principles, with the formerly “free press” reduced to being the propaganda extension of the controlling elites.

The assassination of JFK brought about the end of the American republic analogously to the way the assassination of Julius Caesar by a cabal of wealthy land-owner senators, whose power and influence Caesar had started to break up, brought about the end of the 500-hundred year history of the Roman Republic and was followed by a totalitarian empire. For a fascinating fresh look at that event, read historian Michael Parenti’s The Assassination of Julius Caesar (2003).

David Talbot’s Brothers focuses on the relationship of JFK and Robert Kennedy, who became not only his attorney general, but his most trusted advisory as it became clear that, because of the debacle of the botched Cuban Bay of Pigs invasion he could not trust the Joint Chiefs of Staffs, who were always itching to go to war (that’s what the military always want) and had become his sworn enemies. He also could not trust the CIA (which he said he wanted to “splinter into a thousand pieces”) when he realized they were always pursuing their own subversive agendas in various parts of the world, without any oversight or even truthful disclosure, as required by law. The CIA and their Cuban exile allies wanted to take Cuba back from Castro and were deeply resentful of what they perceived as Kennedy’s failure to follow-up their Bay of Pigs invasion agenda by “sending in the Marines” even though Kennedy had assured them beforehand he had no intention of doing so.

During the Cuban missile crisis, when the entire world came within a hair’s breadth of exchanging nuclear missiles and terminating civilization as we know it, JFK only managed to defuse the situation through his personal back-channel connection to Nikita Krushchev, the Soviet Premier who was similarly being pushed by his military commanders breathing down his neck to let fly the missiles. The two men talked directly, but secretly, by telephone and agreed to turn their respective countries away from war and toward peace. Kennedy and Krushchev thereafter started taking the first, small steps toward a negotiated, gradual disarmament process. As a life-long peace activist, this was to me the most moving and dramatic revelation of Talbot’s book – to know that at the height of maximum tension in the Cold War, these two warriors at the heads of their respective imperial armies reached out and agreed to take steps to avert and avoid war for ever. Immediately after the assassination, Robert Kennedy, who was of course aware of his brother’s plans and activities, took pains to use his own back channel connection with the Kremlin to assure Krushchev that he and the Americans were not blaming the Soviets for his brother’s assassination (knowing that the CIA and the military would have attempted to do just that).

Peter Janney’s book Mary’s Mosaic is about Mary Pinchot Meyer – a woman whom Kennedy really loved (unlike the numerous bimbos his sex addiction brought to his bed) and with whom he came to share his vision of turning the world toward a lasting peace. Mary Meyer was assassinated in a Washington park where she was walking, a few months after the JFK assassination. An uneducated black man walking nearby was arrested and tried for the murder – but acquitted for lack of credible evidence. Since Mary Meyer came from an upper class family and had relatives and friends in high places (her former husband was Cord Meyer, who was a high CIA official) her death occupied the rumor mills for quite a while, but then receded into oblivion as yet another unsolved murder case. Peter Janney, who spent forty years researching this book, had a personal connection to Mary Meyer since he was best friends with her son, who got killed in an automobile accident as a child. And Janney’s father was also a high-ranking CIA official, making with Cord Meyer and James Angleton, a trio of CIA spooks who feature repeatedly in the various conspiratorial scenarios that swirl around the assassinations of the 1960s and beyond.

I found his book incredibly interesting and powerful, blending a poignant story of personal tragedy with stories of outrageous criminality in the highest corridors of the American imperial court. The Mary Meyer murder story, which features briefly in David Talbot’s book and hardly at all in most other Kennedy books is the central focus of Janney’s book, because of his personal connection to her family. My old friend and colleague Tim Leary also features in the Mary Meyer story, although I personally never heard him talk about this connection. (It does not surprise me at all that Leary would keep his contacts with Mary secret, at her request). In his autobiography Flashbacks, Leary relates that Mary came to see him in 1962-63, seeking guidance on how to guide LSD sessions for a small group of Washington insider wives, who were wanting to turn the world system to world peace. They had a few meetings, Mary reported that things were going well – but then something happened that alarmed her, her peace conspiracy had been discovered. She warned Leary to lie low, they lost contact. Then in November 1963, JFK was killed, three or four months later Mary Meyer was killed. Many people believe that Mary kept a diary of her meetings with JFK, which the CIA and others were anxious to retrieve.

Regardless of whether there was a diary in which Mary described her affair with the President and/or his designs for peace – a supposition that I for one find unlikely, given the woman’s obvious understanding of the explosiveness of their thinking if it was revealed prematurely or at all. Janney’s book includes a description of a never-before published two-hour interview of Tim Leary and what he knew about Mary Meyer, conducted by Leo Damore (himself an assassination researcher who died of a sudden brain tumor before he could finish his own book) in 1990 (i.e. more than forty years after the assassination) confirming much of the story Leary told in Flashbacks, and adding details.

The conclusions emerging from this book are staggering –Kennedy and the only woman he truly loved took LSD together in the White House, conceiving and birthing their vision for world peace and how to bring it about. As Janney writes, explaining his concluding understanding of why she was killed, –

After Dallas, amid utter horror and shock, Mary had taken it upon herself to to discover and make sense of the truth of the conspiracy that had taken place – only to realize the magnitude of the second conspiracy, a cover-up taking place right before her eyes.. It was her own mosaic of people, events, circumstances, and exploration that informed her understanding – not only of the evil that had taken place in Dallas, but of the villainous darkness that was now enveloping all of America. She had furiously confronted her ex-husband, Cord Meyer, possibly Jim Angleton as well, with what she had discovered, not fully realizing the extent of their own diabolical ruthlessness. The Warren Report was nothing but a house of cards; once ignited, it would be engulfed in flames. If Mary courageously went public with who she was, and what she knew, making clear her position in the final years of Jack’s life, people with influence would take notice; the fire of suspicion around Dallas would erupt into a conflagration. She had to be eliminated (p. 391).

This book shines a brave and brilliant light of truth into a still dark and somber chapter of American history (irrespective of whether the story he tells is precisely true in all its details), a crucial turning point on the pathway from republican democracy to military empire, a pathway on which he are still marching, blinded by fear and ignorance. May these two books (and others now coming out about the Kennedy era) contribute to our awakening and a returning to sanity.

CIA, LSD and Chemical Warfare – Part II

In my blog dated Jan 23, 2012, I reported a story from the UK Telegraph, by investigative journalist H.P. Albarelli,  on covert CIA experiments with LSD, which allegedly resulted in an incident of mass ergot poisoning through contaminated bread in the French village Pont-Saint-Esprit in 1951.

I should have known better than to uncritically accept a story involving the CIA, the undisputed world masters at disinformation propaganda. Dieter Hagenbach, co-author of the recently published authoritative biography of Albert Hofmann, wrote to tell me that they investigated this story. Here, in extract, is what he and his co-author Lucius Werthmüller,  found. (Albert Hofmann und sein LSD, published by AT Verlag, 2011, has not as yet come out in an English translation).

The authors relate that Albert Hofmann and Werner Stoll,  the two Sandoz scientists most knowledgeable about ergot alkaloids and toxicity travelled to France in 1951, and talked to French research chemist Henri Olivier in Marseille, as well as physicians and psychiatrists who had investigated the epidemic and several of the patients who had suffered the symptoms of the pain maudit, the “cursed bread” as it was called. The chemical analyses and medical symptoms had led to a provisional conclusion of an ergot toxicosis.

Hofmann and Stoll took several kilograms of the flour and 600 grams of the bread that had been consumed in the episode in order to subject it to exhaustive chemical and toxicological analyses. The results were contradictory: a chemical analysis suggested the toxicity came from a mercury-containing seed-stock disinfectant, while a psychiatrist concluded the psychological symptoms resembled ergot poisoning. Albert Hofmann wrote in his concluding report to his superiors that “on the basis of the colorimetric analyses of the three samples, none of them contained ergot alkaloids.” Thus, the effects found in Pont-Saint-Esprit “remain a mystery. Neither LSD nor mercury produce the kinds of symptoms that had been reported. LSD does not produce intense toxic, organic reactions nor do the intense hallucinations reported correspond to any known forms of mercury poisoning.” (op.cit. p.99). They also pointed out that LSD could not have been involved in the poisoned bread since LSD dissolves rapidly in air and upon exposure to sunlight, or upon being dissolved in water, or being baked in bread.

Hagenbach and Werthmüller further discuss the sensationalist account of the episode found in a 2009 book by H.P. Albarelli – which had raised the possibility that the Pont-Saint-Esprit episode was part of  secret CIA cold war experiments with mass poisonings by anthrax and other biological warfare agents carried out under the direction of Frank Olson in the US Army laboratories at Fort Detrick in the 1950s. The actual nature of his work was, and remained, top-secret.  What is known is that Olson became horrified by the work that he was participating in. He either committed suicide or was pushed out of a window in New York, after being surreptitiously dosed with LSD by other CIA agents in 1953. A wrongful death case brought by his widow and family resulted in 1975 in a payment $750,000, together with an invitation to the White House where President Gerald Ford and CIA-Director William Colby personally apologized to the family. The exact details of the work he was involved in or how he was poisoned have remained secret. A website exists that is still accumulating data and reports relating to his case.

Hagenbach and Werthmüller concluded that “a connection between Frank Olson and Albert Hofmann or Sandoz cannot be found, and Hofmann’s diaries do not support even the slightest suspicion that he and Stoll had participated in an investigation of a secret CIA action.”

Despite Hofmann and Stoll’s conclusive rejection of any possible connection between the Pont-Saint-Esprit episode and LSD, a 1968 book by John G. Fuller – The Day of Saint Anthony’s Fire – repeated the same fabrication, with embellishments. New York psychiatrist John Beresford, MD (1924-2007; who was known to and friends with Leary, myself and the Harvard researchers, and who later dedicated himself to working with people that had been unjustly incarcerated as victims of America’s punitive drug-war laws) was troubled by the implications suggested in Fuller’s book and wrote to Hofmann concerning the concerns it raised for him. Hofmann replied in a letter to Beresford, using unmistakeably indignant language.

“The citations in John Fuller’s book The Day of Saint Anthony’s Fire are invented fictions as is the great majority of what he wrote in this book. .. The whole work is a scandal. It has been proven conclusively that ergot was not involved in the Pont-Saint-Esprit episode. Mr Fuller must have known this fact. … To mention just one fact that shows the falsehood of Fuller’s writing – LSD is a semi-synthetic product, that occurs as such neither in ergot nor anywhere else in nature. …Mr Fuller has misused ergot, St. Anthony’s Fire and LSD in order to try to write a best-selling work.” (Hagenbach & Werthmüller, p. 101).

CIA used LSD in covert chemical warfare experiments

New evidence has surfaced to add to the catalog of nefarious methods tested by the CIA during the Cold War.  Many of such experiments were exposed in Martin Lee’s 1986 book Acid Dreams: The CIA, LSD and the Sixties Rebellion.  In an article published in the  U.K. Telegraph, H P Albarelli Jr., an investigative journalist, claims the outbreak resulted from a covert experiment directed by the CIA and the US Army’s top-secret Special Operations Division (SOD) at Fort Detrick, Maryland.

In 1951, a quiet, picturesque village in southern France was suddenly and mysteriously struck down with mass insanity and hallucinations. At least five people died, dozens were interned in asylums and hundreds afflicted.  … The mystery of Le Pain Maudit (Cursed Bread) still haunts the inhabitants of Pont-Saint-Esprit, in the Gard, southeast France. The inhabitants were suddenly racked with frightful hallucinations of terrifying beasts and fire.

An American investigative journalist has uncovered evidence suggesting the CIA peppered local food with the hallucinogenic drug LSD as part of a mind control experiment at the height of the Cold War.

One man tried to drown himself, screaming that his belly was being eaten by snakes… Many were taken to the local asylum in strait jackets. Time magazine wrote at the time: “Among the stricken, delirium rose: patients thrashed wildly on their beds, screaming that red flowers were blossoming from their bodies, that their heads had turned to molten lead.”

Eventually, it was determined that the best-known local baker had unwittingly contaminated his flour with ergot, a hallucinogenic mould that infects rye grain.  Note: LSD is a semi-synthetic derivative of ergot; ergotamine, also derived from ergot, is used in obstetrics) Both were produced by the Swiss-based Sandoz Pharmaceutical Company, which was then secretly supplying both the Army and CIA with LSD for their chemical warfare experiments.

The Telegraph story continues..

Mr Albarelli came across CIA documents while investigating the suspicious suicide of Frank Olson, a biochemist working for the SOD who fell from a 13th floor window two years after the Cursed Bread incident. One note transcribes a conversation between a CIA agent and a Sandoz official who mentions the “secret of Pont-Saint-Esprit” and explains that it was not “at all” caused by mould but by diethylamide, the D in LSD.

While compiling his book, A Terrible Mistake: The Murder of Frank Olson and the CIA’s Secret Cold War Experiments, Mr Albarelli spoke to former colleagues of Mr Olson, two of whom told him that the Pont-Saint-Esprit incident was part of a mind control experiment run by the CIA and US army. …

Mr Albarelli said the real “smoking gun” was a White House document sent to members of the Rockefeller Commission formed in 1975 to investigate CIA abuses. It contained the names of a number of French nationals who had been secretly employed by the CIA and made direct reference to the “Pont St. Esprit incident.”

In its quest to research LSD as an offensive weapon, Mr Albarelli claims, the US army also drugged over 5,700 unwitting American servicemen between 1953 and 1965.

None of his sources would indicate whether the French secret services were aware of the alleged operation. According to US news reports, French intelligence chiefs have demanded the CIA explain itself following the book’s revelations. French intelligence officially denies this.

Locals in Pont-Saint-Esprit still want to know why they were hit by such apocalyptic scenes.

Share: http://www.telegraph.co.uk/news/worldnews/europe/france/7415082/French-bread-spiked-with-LSD-in-CIA-experiment.html

Comic clip on the “stoned ape theory” of human evolution

My friend, the late evolutionary philosopher Terence McKenna, was celebrated for his elegantly humorous discourses on the consciousness-expanding virtues of psychedelic mushrooms. Audio and video recordings of his talks are pervasive on the internet. He also made a serious contribution to the theory of human evolution by postulating that the accidental ingestion of hallucinogenic, consciousness-expanding mushrooms by our hominid ancestors may have contributed to the accelerated development of language and brain function. He expands on this view in his 1992 book Food of the Gods – The Search for the Original Tree of Knowledge.

In the introduction to my edited book of essays and experiences Sacred Mushroom of Visions – Teonanácatl, I wrote of four lines of empirical evidence supporting the theory that mind-expanding plants or fungi may have played a role in the evolution of language: (1) psilocybin and other psychedelics heighten acuity of sense perception, which confers adaptive advantage; (2) psilocybe mushrooms heighten cognitive awareness and linguistic fluidity; (3) they also enhance problem-solving ability as shown in their successful use in psychotherapy and shamanic divination; and (4) studies of brain areas activated during psilocybin states show major activity in the frontal cortex, the area most involved in processing complex perceptions and thoughts.

I quoted the following passage also from McKenna’s Food of the Gods, where he is discussing the significance of the discovery of cave paintings in North Africa pointing to a pre-historic mushroom cult in the 7th millenium BCE:

“The contention here is that the rise of language, partnership society, and complex religious ideas may have occurred not far from the area where humans emerged – the game-filled, mushroom-dotted grasslands and savannahs of tropical and subtropical Africa. There the partnership society arose and flourished; there hunter-gatherer culture slowly gave way to domestication of animals and plants. In this milieu the psilocybin-containing mushrooms were encountered, consumed and deified. Language, poetry, ritual, and thought emerged from the darkness of the hominid mind.” (McKenna 1992).

While McKenna’s theory on the role of psychoactive mushrooms in the human evolution of language has not gained much traction in the scholarly community (understandedly, since the great majority of scholars and evolutionary scientists are ignorant of the profound effect of such substances on the human mind), it has attracted a following in the underground entheogenic culture of scientists, artists, philosophers and cyber-geeks, as shown in the following two minute YouTube clip from Duncan Trussell’s Comedy Central Pilot “Thunderbrain.”

Some interesting facts about cannabis and its usage in America

At a recent conference of the Drug Policy Alliance – a public education and advocacy group doing excellent work – I was made aware  and/or reminded of some starling yet established facts concerning the ancient and sacred healing herb cannabis.

Prevalence and usage

# 42% of the US population age 12 and older admits to trying cannabis at least one time. This equates to about 100 million people.

# The percentage of Americans favoring cannabis legalization is the highest it has been in 40 years: 41% think it should be legal.

# 75% of Americans favor legalization of medical cannabis use.

# White people consume and sell cannabis at the same rate as African-Americans.

# Domestic production of cannabis in the US is estimated at 20 million pounds per year – higher than at any time in history.

# Mexican drug cartels make up to 80% of their profits from cannabis exported to the US.

# The value of the annual cannabis crop exceeds the value of wheat, cotton and corn combined, making cannabis by far the most valuable agricultural commodity in the US.

# The high monetary value of the cannabis crop is in large measure due to the high price paid for the cannabis harvest, in comparison to the other food crops. This high cost of the cannabis harvest in turn is a function of its illegal status, requiring all kinds of unusual risk-protection measures to be in place. So, if it were legalized the price of the crop is likely to decline significantly.

Prohibition and its costs, potential consequences of its repeal

# 900,000 Americans were arrested in the last year for crimes related to cannabis.

# African-Americans are twice as likely to be arrested as Whites (though usage is the same).

# In California, African Americans make up less than 7% of the population but 22% of those arrested for marihuana offenses, 33% of marihuana-related felony offenses.

# Nearly one half of all prisoners in America are serving sentences for drug related offenses.

# This amounts to about half a million prisoners at an average cost of $40,000 per year per prisoner.

# There are more than 50,000 police paramilitary raids in the US every year  – more than 130 every day. Virtually all are for prosecution of drug warrants, the vast majority involving marihuana.

# Many jurisdictions use heavily armed and armored SWAT teams for execution of drug search warrants. (Comment/Question: are they practicing and testing their latest equipment?)

# Legally regulated cannabis would save $7.7 billion in

government expenditures on prohibition: $2.4 billion at the federal level and $5.3 billion at the state and local level.

# Revenue from taxation of cannabis sales could range from an estimated $2.4 billion per year if taxed like ordinary consumer goods, to $6.2 billion if taxed  like alcohol or tobacco.

Medical/clinical aspects

# A DEA Administrative Law judge declared in 1988 that “Cannabis is one of the safest therapeutically active substancs known to man…In strict medical terms, marihuan is far safer than many foods we commonly consume.

# In 2007 researchers studied the effects of THC on uses suffering from depression asnd found that moderate doses had an anti-depressant effect, but heavy doses could exacerbate depression.

# Studies in 2003 and 2007 concluded that cannabis does not appear to be causally related to schizophrenia, but that its use could precipitate psychological disorders in people vulnerable to developing psychoses.

# Cannabis smokers can have similar respiratory problems as tobacco smokers, including cough and phlegm production, more frequent acute chest illness and a heightened rist of lung infection. However, a 2006 study funded by NIDA found that smoking cannabis, even regularly and heavily, does not lead to lung cancer.

# Researcers at UCLA and UCSF determiend that THC.. has an anti-tumor effect.

# The FDA has found THC to be safe and effective for the treatment of nausea, vomiting

Psychedelic Research Projects on Dying and on Autism Are Seeking Funding Support

Some of the most innovative and significant research on psychedelics within the medical/psychiatric establishment has been done by Charles Grob, M.D. at the Harbor-UCLA Medical Center in Los Angeles. Dr. Grob also collaborated with Dennis McKenna, Ph.D., J.C. Callaway, Ph.D. and scientific researchers associated with the UDV, one of the Brazilian ayahuasca churches, on psychological and physical effects of long-term use of ayahuasca. These studies were published in the medical-scientific literature and also described in three chapters by these researchers in my edited book on Ayahuasca – Sacred Vine of Spirits.

Doing research on dying, or even speaking openly about one’s death, is generally avoided due to the unspoken taboo which obstructs a reasoned and compassionate look at the unavoidable fact that living is a terminal condition  – with or without illness. Following suggestions from Aldous Huxley and pioneering research by Stanislav Grof, MD in the sixties on using psychedelics to relieve end-of-life anxiety, Charles Grob has done follow-up research on this area as well.

A study of using psilocybin to relieve anxiety in terminal patients with advanced stage cancer was published recently in the journal Archives of General Psychiatry considered the #1 impact publication in the field of psychiatry. (Grob, C.S, et al.  A pilot study of psilocybin treatment for anxiety in advanced-stage cancer patients.)

Charles Grob and his colleague Roland Griffiths also published an overview article on this work in the prestigious Scientific American (Dec 2010) Hallucinogens as Medicine  which is a major sign that scientific research on psychedelics is again entering a new phase of establishment acceptance after two decades of prohibition and neglect.

Establishment acceptance and FDA/DEA permission, though they are necessary preconditions for new research in this area,  are not sufficient since such research on unpatentable substances does not attract funding from pharmaceutical companies who are primarily attentive to their bottom line.

Dr. Charles Grob has written that

My colleagues and I at have completed a landmark clinical research study using a psilocybin treatment model in patients with advanced-stage cancer anxiety. We are now confident that we will be able to extend our investigations and further contribute to this long-neglected yet now resurrected field. We are eager to implement a modified treatment protocol that will allow us to utilize a somewhat higher dosage of psilocybin as well as the option to treat the subject with a second “booster” session several weeks after the first. However, as the national granting agencies have historically declined to support psychedelic research studies, it has become essential to solicit our funding from private donors. So, I am contacting you to explore whether you might be able to help us with funding support.

To get a sense of the significance and potential impact of this work with psilocybin in alleviating anxiety around dying, below are  are links to two filmed interviews with subjects who went through this program, and who have since died.

http://www.doc-jukebox.com/film/medical-research-psychedelics/annies-psilocybin-therapy

http://www.heffter.org/research-hucla.htm

A second research project that Dr. Charles Grob is initiating involves using a novel phenethylamine analog in treating autism. This area was also pioneered in the 1960s (and subsequently dropped) when psychologist Gary Fisher, Ph.D. working at Fairview State Hospital in Orange County, gave small doses of LSD to hospitalized autistic children – with some remarkable results. Charles Grob writes as follows about this project:

I also wanted to alert you to a second study for which we are in the early planning stages and that we believe may have great potential for further development and application in the future. This is a study using a psychedelic phenethylamine analogue to treat individuals who are considered to have Asperger’s Disorder, also known as Autism Spectrum Disorder. Given the serious lack of effective treatment, and the growing numbers of young people identified with this developmental delay condition, there is no doubt a compelling need for a new therapeutic approach. Unlike our psilocybin treatment of anxiety in individuals with advanced medical illness, for which we have demonstrated feasibility and safety and have already completed our pilot clinical study, the psychedelic phenethylamine analogue study will need to be developed in its entirety, from drug preparation to pre-clinical toxicology studies to Phase 1 human investigations. Obviously, this will require greater time and expense to develop, yet we believe that this project has great potential for the vast numbers of individuals with this condition.

I’ve had a compelling interest in the potential of psychedelics to impact our culture and medical practice for more than forty years and believe that the obstacles that held the field back in the past have lifted, making it possible to explore this fascinating and potentially valuable area of research. The rate limiting factor no longer appears to be government regulators, but rather the financing of the actual studies. We have made enormous progress over the last few decades to get to this point, and are now poised to extend our work to a substantive degree. We hope you will be able to help us in this endeavor.

Dr. Grob has told me that they are seeking to raise about $150,000 for an extended follow-up study on psilocybin and end-of-life anxiety; and another $300,000 for the phenethylamine analogue autism study – more expensive since the researchers need to begin with pilot and feasibility studies in this area. The research facility where the work would be carried is a non-profit institution and can accept tax-deductible donations. It would also be possible to channel funds for these projects through the non-profit Green Earth Foundation. To learn more about these research projects and how to support them please contact Dr. Charles Grob at cgrob@labiomed.org

Meanwhile…regressive drug policies still hold sway in the UK (as well as USA)

The following article on drug policy in the UK appeared in The Guardian:

British government science advisor sacked for speaking truth about drugs and dangers.

Professor David Nutt, the government’s chief drug adviser, has been sacked a day after claiming that ecstasy and LSD were less dangerous than alcohol…

Nutt incurred the wrath of the government when he claimed in a paper that alcohol and tobacco were more harmful than many illegal drugs, including LSD, ecstasy and cannabis…

..Nutt had criticised politicians for “distorting” and “devaluing” the research evidence in the debate over illicit drugs. Arguing that some “top” scientific journals had published “horrific examples” of poor quality research on the alleged harm caused by some illicit drugs, the Imperial College professor called for a new way of classifying the harm caused by both legal and illegal drugs.

“Alcohol ranks as the fifth most harmful drug after heroin, cocaine, barbiturates and methadone. Tobacco is ranked ninth,” he wrote in the paper from the centre for crime and justice studies at King’s College, London, published yesterday.

“Cannabis, LSD and ecstasy, while harmful, are ranked lower at 11, 14 and 18 respectively.”

Nutt said tonight he was disappointed by the decision but linked it to “political” considerations. “It’s unusual political times, I suppose, elections and all that. It’s disappointing,” he told Sky News. “But politics is politics and science is science and there’s a bit of a tension between them sometimes.”

Nutt clashed with Jacqui Smith when she was home secretary after he compared the 100 deaths a year from horseriding with the 30 deaths a year linked to ecstasy.

He criticised Smith’s use of the “precautionary principle” to justify her decision to reclassify cannabis and said that by erring on the side of caution politicians “distort” and “devalue” the research evidence.

“This leads us to a position where people really don’t know what the evidence is,” he said adding that the initial decision to downgrade the classification of cannabis led to a fall in the use of the drug.

…Nutt also renewed his support for reclassifying ecstasy from a class A drug to class B, saying the advisory committee “won the intellectual argument” over the issue but obviously didn’t win the decision after the home secretary vetoed the move.

Richard Garside, director of the centre for crime and justice, said Nutt’s briefing paper gave an insight into what drugs policy might look like if it was based on the research evidence rather than political or moral positioning.

Garside added: “I’m shocked and dismayed that the home secretary appears to believe that political calculation trumps honest and informed scientific opinion. The message is that when it comes to the Home Office’s relationship with the research community honest researchers should be seen but not heard.

“The home secretary’s action is a bad day for science and a bad day for the cause of evidence-informed policy making.”

It’s important to recognize that the rankings of harmfulness are based on the ill-health effects on the individual of the various drugs. If one calculates the cost to society, where you are considering the number of people who are taking these drugs you end up with a different ranking. In the United State (and perhaps other countries) in terms of public health harm to society, tobacco and alcohol far out-rank every other drug, legal or illegal, as has been well-known for decades.

http://www.guardian.co.uk/politics/2009/oct/30/drugs-adviser-david-nutt-sacked?INTCMP=ILCNETTXT3487

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